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A Pulsed Electrical Joint Stimulator for the Treatment of Osteoarthritis of the Hand and Wrist.

Orthopedics. 2018 May 29:1-7. doi: 10.3928/01477447-20180524-01. [Epub ahead of print]

Holt PAOzyurekoglu TDeveshwar SMaclaughlin EJKhlopas AMont MAPang SWTuber JSSchechtman JZizic TM.


The hand is commonly affected by osteoarthritis (OA). The development and progression of OA are believed to involve inflammation, even in the early stages of the disease. Inflammatory and proinflammatory cytokines have also been shown to be elevated in the flexor tenosynovium of idiopathic carpal tunnel syndrome (CTS). A large percentage of patients with hand OA also have a concomitant CTS. This study evaluated the results of a pulsed electrical joint stimulator in patients who had hand OA with or without CTS. Pain, tenderness, and swelling; grip strength and pinch force; and Patient and Physician Global Assessment and Disabilities of the Arm, Shoulder and Hand (DASH) results were evaluated. The primary efficacy outcome was pain due to OA in the study hand in the past 48 hours. Secondary outcomes consisted of OA pain in the study thumb in the past 48 hours, grip strength, pinch force, and Patient and Physician Global Assessment and DASH results. All 7 outcome parameters improved in OA patients. On physical examination, individual finger and wrist joints had also improved regarding pain, swelling, and tenderness. In the subset of patients with CTS, CTS pain, paresthesia, weakness, and all CTS symptoms had significantly improved. Patient and Physician Global Assessment and DASH results and pinch force were also significantly improved. This pulsedelectrical joint stimulator is effective in providing clinically relevant and statistically significant reductions in the signs and symptoms of OA of the hand and CTS. It could be a useful modality for the treatment of patients who have one of these conditions or both. [Orthopedics. 201x; xx(x):xx-xx.].

PMID:  29813168

DOI:  10.3928/01477447-20180524-01


PubMed link: https://www.ncbi.nlm.nih.gov/pubmed/?term=Pulsed+Electrical+Joint+Stimulator+for+the+Treatment+of+Osteoarthritis

Citation for 1999 Zizic Study

80% Greater Improvement

in patient evaluation of function

73% Greater Improvement

in patient evaluation of pain and symptoms

40% Improvement

in disease activity

Zizic et al. The Treatment of Rheumatoid Arthritis of the Hand with Pulsed Electrical Fields. Electricity and Magnetism in Biology and Medicine. Bersani, Kluwer Academic/Plenum Publishers, 1999.

Citation for Current Orthopedics Study:

35% Reduction in hand and thumb
pain on OA patients

A significant reduction of:
hand and thumb pain

BioniCare has large effect on patient pain and symptoms and in reducing the severity of disease.

Holt PA, Ozyurekoglu T, Deveshwar S, Maclaughlin EJ, Khlopas A, Mont MA, 
Pang SW, Tuber JS, Schechtman J, Zizic TM.